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Yellow nail syndrome (also known as "Primary lymphedema associated with yellow nails and pleural effusion") is a very rare medical syndrome that includes pleural effusions, lymphedema (due to lymphatic hypoplasia) and yellow dystrophic nails. Approximately 40% will also have bronchiectasis. It is also associated with chronic sinusitis and persistent coughing. It usually affects adults.〔(【引用サイトリンク】title=Yellow nail syndrome. DermNet NZ )〕〔Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.〕 Restated, yellow nail syndrome is characterized by marked thickening and yellow to yellow-green discoloration of the nails often associated with systemic disease, most commonly lymphedema and compromised respiration.〔 Although it has an OMIM number, it has been suggested that it might not have a genetic link. There is some evidence it may be caused by titanium, either implanted for medical reasons or through eating various foods containing titanium dioxide. In patients where titanium exposure was thought to be causative, recovery occurred over a period of several months. ==Treatment== Dramatic improvement in nail discoloration is achieved by oral clarithromycin. Normal treatment for swelling and any respiratory problems is appropriate. Nutritional supplementation with Vitamin E in some studies has been shown to be effective in controlling nail changes.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「yellow nail syndrome」の詳細全文を読む スポンサード リンク
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